Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programs
نویسندگان
چکیده
منابع مشابه
Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programs
Epithelial-mesenchymal transition (EMT) is required for mesodermal differentiation during development. The zinc-finger transcription factor, Snail1, can trigger EMT and is sufficient to transcriptionally reprogram epithelial cells toward a mesenchymal phenotype during neoplasia and fibrosis. Whether Snail1 also regulates the behavior of terminally differentiated mesenchymal cells remains unexpl...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2009
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.200810113